How Sildenafil Citrate Works in the Body

Sildenafil > sildenafil 50 mg tab


The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

  • Sildenafil 50 mg may cause flushing and nasal stuffiness.
  • Do not use if allergic to sildenafil or similar drugs.
  • Patients should discuss health history before use.
  • It may take longer to work in some individuals.
  • Do not use as a performance enhancer.
  • Avoid using other medications without doctor approval.
  • Keep a record of any side effects experienced.
  • Inform your doctor if you are pregnant or breastfeeding.

Using this medicine with any of the following medicines is not recommended.

In case of emergency/overdose

Sildenafil should never be used in children for erectile dysfunction. In general, sildenafil should not be used for pulmonary arterial hypertension in children, especially for chronic use. Use of sildenafil oral film is not indicated for use in the pediatric population. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sildenafil in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving sildenafil.

Mechanism of Action

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases.

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If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain oral sildenafil medicines may also cause interactions to occur. Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: Abnormal penis, including a curved penis or birth defects of the penis—Chance of problems occurring may be increased and this medicine should be used with caution in these patients. Arrhythmia (irregular heartbeat, within the last 6 months) or Blood vessel problems (eg, aortic stenosis, idiopathic subaortic stenosis) or Heart attack (within the last 6 months) or Retinitis pigmentosa (an inherited eye disorder) or Stroke (within the last 6 months)—Should not be used in patients with these conditions. Crowded disc or low cup to disc ratio in the eye (an eye disorder) or Hyperlipidemia (high fats in the blood) or Non-arteritic anterior ischemic optic neuropathy or NAION (serious eye condition), history of or Retinitis pigmentosa (an inherited eye disorder) or Smoking—May increase the chance for a serious side effect in the eye called NAION. Stomach ulcer, or history of or—Chance of problems occurring may be increased. It is not known if the medicine is safe for use in these patients. The effects may be increased because of slower removal of the medicine from the body. Sickle-cell anemia (blood disorder)—Sildenafil should be used with caution in these patients as problems with prolonged erection of the penis may occur. Pulmonary arterial hypertension (high blood pressure in the lungs) or Pulmonary veno-occlusive disease or PVOD (a type of lung disease)—Use with caution. Use sildenafil exactly as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. If too much is used, the chance of side effects is increased. This medicine comes with a patient information leaflet. Read and follow these instructions carefully before you start using sildenafil and each time you get a refill of your medicine.

What does Eroxon Gel contain

Sildenafil works on the PDE5 enzyme in the lungs to relax the blood vessels. This will increase the supply of blood to the lungs sildenafil tablet manforce 50 mg and reduce the workload of the heart. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make.

What are the serious side effects of sildenafil?

For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects of sildenafil in children younger than 1 year of age. Safety and efficacy have not been established. Ask your doctor if you have any questions. You may take this medicine with or without food.

  • Sildenafil can cause side effects like dizziness.
  • Use with caution if you have liver or kidney issues.
  • The medication may cause vision changes or blurriness.
  • Take sildenafil on an empty stomach for quicker effect.
  • Follow your doctor’s dosage instructions strictly.
  • Overdose may lead to serious health complications.
  • Avoid driving or operating machinery after taking.
  • Use only the prescribed strength, 50 mg.

Place the film on top of your tongue. It will dissolve in your mouth and can be swallowed with saliva without using water or other liquids. Shake the bottle well for at least 10 seconds before each use. Remove the cap by pushing it down and twisting it counter-clockwise.

More about sildenafil

Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection.

Who should not take sildenafil?

By controlling the enzyme, sildenafil helps to maintain an erection after the penis is stroked. Without physical action to the penis, such as that occurring during sexual intercourse, sildenafil will not work to cause an erection. Sildenafil is also used in both men and women to treat the symptoms of pulmonary arterial hypertension. This is a type of high blood pressure that occurs between the heart and the lungs. When hypertension occurs in the lungs, the heart must work harder to pump enough blood through the lungs. Push the plunger of the syringe, then insert the tip into the bottle while holding the bottle upright on a flat surface. Slowly pull back the plunger until the required dose. If you see air bubbles in the syringe, repeat the steps. Place the tip of the syringe into you or your child's mouth and point it towards the cheek. This medicine usually begins to work for erectile dysfunction within 30 minutes after taking it. It continues to work for up to 4 hours, although its action is usually less after chew sildenafil 2 hours. Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.

Use Case Description Typical Dosage Notes
Erectile Dysfunction Improve erectile response during sexual activity 50 mg as needed Taken 30-60 min before activity
Pulmonary Arterial Hypertension Off-label use to reduce blood pressure in lungs Under medical supervision Brand: Revatio
Off-label uses Possible off-label benefits in other circulatory disorders Under research Not generally approved

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For treatment of erectile dysfunction:For oral dosage form (tablets):Adults up to 65 years of age—50 milligrams (mg) as a single dose no more than once a day, 1 hour before sexual intercourse.

Side Effect Frequency Severity Management Tips
Headache Common Mild to moderate Analgesics, hydration
Flushing Common Mild Cooling measures, hydration
Nasal Congestion Common Mild Use decongestants cautiously
Dizziness Less common Mild to moderate Avoid operating machinery
Visual Disturbances Rare Mild to moderate Discontinue if persistent
Priapism Rare Severe Immediate medical attention

Alternatively, the medicine may be taken 30 minutes to 4 hours before sexual intercourse. Your doctor may adjust your dose if needed.Adults 65 years of age and older—25 mg as a single dose no more than once a day, 1 hour before sexual intercourse.

Further information

However, it can also be used to treat Raynaud's phenomenon, a condition in which the fingers and toes become cold and numb due to reduced blood flow. Additionally, sildenafil 100 mg tablets can be used to treat certain types of glaucoma, as well as to improve exercise capacity in people with heart failure. When using sildenafil 100 mg tablets, it is important to follow the instructions of your doctor or pharmacist. It is also important to be aware of any potential side effects, such as headache, flushing, dizziness, and nausea. If you have any questions about the use of sildenafil 100 mg tablets, please reach out to us at Bayview Pharmacy.

Cessation and Adverse Effects of Treatment

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.No compounded medications are reviewed by the FDA for safety or efficacy. No compounded medications are reviewed by the FDA for safety or efficacy. Sildenafil is used to treat erectile dysfunction (also called sexual impotence). Your doctor may adjust your dose if needed.Children—Use is not recommended.For oral dosage form (film):Adults up to 65 years of age—50 milligrams (mg) as a single dose no more than once a day, 1 hour before sexual intercourse.

  • Sildenafil 50 mg is available by prescription only.
  • Store tablets in a cool, dry place away from sunlight.
  • Do not use with nitrate medications to prevent risk.
  • Seek medical advice if you have heart problems.
  • It may interact with other medications like antihypertensives.
  • Not recommended for women or children.
  • The tablet should be swallowed whole with water.
  • Do not crush or chew the tablet.

Your doctor may adjust your dose as needed.Adults 65 years of age and older—25 mg as a single dose no more than once a day, 1 hour before sexual intercourse.