Sildenafil cream for female sexual arousal disorder available to prescribe in select states

Daré Bioscience on Wednesday launched Dare to Play, a first-of-its-kind prescription cream designed to enhance blood flow to female genital tissue.

Arousal Cream FAQs

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I truly can’t thank you enough for caring about women, our satisfaction and health. Menopausal women deserve generic viagra sildenafil citrate 50 mg to have a satisfying sex life. I've always had trouble having an orgasm. Trying different types of arousal lubricants didn't provide me any better of an experience. I came across WISP and the OMG Cream researching different ways to achieve orgasms.

Estradiol Vaginal Cream

I was able to climax multiple times. I was blown away because I've never experience anything like this. I know that everybody is different, but this product worked very well for me. I never had an issue with arousal, it was just never being able to climax. This cream helped to push me over the edge. The topical treatment — which contains sildenafil, the same active ingredient in Viagra — is filling a long-overlooked need. Studies show that women experience sexual dysfunction as much as men, and it can be treated with similar drug mechanisms, said Sabrina Martucci Johnson, president and CEO of Daré Bioscience. “We have this scientific evidence that sildenafil as an active ingredient can work if only it were designed and formulated specifically with women in mind,” Johnson told The Post, “and that’s really then where we came into the equation.” Research indicates that over 40% of women experience some form of sexual dysfunction, with arousal difficulties a common complaint. The problem — known formally as female sexual interest/arousal disorder (FSIAD) — could arise from several issues, including hormonal changes from pregnancy or menopause, stress, medication use, diabetes, depression or past sexual abuse.

To combat FSIAD, women might try psychotherapy, stress reduction techniques or flibanserin, a medication that works by balancing the brain chemicals serotonin, dopamine and norepinephrine to enhance sexual desire. Dare to Play targets the physical symptoms of FSIAD by helping blood vessels in the clitoris and vulva relax and open, increasing genital blood flow and improving lubrication and swelling responses. “It’s the blood flow that goes to the genital tissue that causes tingling, warmth, engorgement,” Johnson said. “It actually is what leads to the lubrication response in arousal in women, because that’s all mediated from the blood flow to the tissue.” Dare to Play has been in the works for many years.

• Viagra cream is often used by men seeking a discreet option.
• It is a semi-liquid formulation that enhances intimacy.
• The cream may be combined with other topical agents.
• Its shelf life depends on storage conditions.
• Usually available through online vendors, sometimes unregulated.
• The safety and efficacy of Viagra cream are not FDA-approved.
• Users should consult a healthcare provider before use.
• Possible side effects include skin irritation or headache.
• The dosage can vary depending on the product formulation.
• Use with caution if taking nitrates or other medications.

Early research showed sildenafil could potentially help women with sexual dysfunction, as Viagra has helped men, Johnson said. But a female pill would require a lot of sildenafil, much higher doses than men need, making that option “just not practical,” she added. Daré Bioscience spent about a decade developing a fast-absorbing product that could quickly, easily and safely meet the needs of women — no muss, no fuss. The cream is said to work 10 to 15 minutes after being applied to the genital area. In clinical trials, Daré Bioscience found that arousal, desire and orgasms improved with Dare to Play, and there were no side effects compared to a placebo cream. It was even tested in oral sex situations.

Common Viagra side effects, which are typically mild and temporary, generally include headaches, flushness, indigestion, vision problems and nasal congestion.

• Viagra cream may be marketed with claims of increased stamina.
• It can be part of a broader sexual wellness routine.
• Some products include herbal or natural extracts.
• Expect varying degrees of success based on individual factors.
• Use in combination with foreplay can enhance results.
• It is not a substitute for medical treatment of ED.
• Some formulations require refrigeration for storage.
• Discontinue if adverse reactions happen promptly.
• The cream should be used responsibly and ethically.
• Do not rely solely on topical products for ED issues.

“You’re really not seeing any of the side effects that you might see with like a Viagra that are sildenafil side effects because of the way we’re delivering the product topically, just right where she needs it, so you’re not getting that systemic exposure,” Johnson said. But just like Viagra, Dare to Play is not for everyone. Women with heart conditions or an active herpes outbreak should avoid use.

• Viagra cream can provide localized effects on erectile tissue.
• It might offer quicker results than oral medications.
• Some products claim longer-lasting erections with topical use.
• Topical application reduces the risk of some systemic adverse effects.
• Efficacy reports are anecdotal; clinical trials are limited.
• Proper application involves a gentle massage into the skin.
• Dosage instructions are essential for safety and effectiveness.
• Not recommended for use by women or children.
• Some products may contain unverified or unsafe ingredients.
• Always verify the legitimacy of the product before purchase.

The good news is that you don’t need an official FSIAD diagnosis to get the prescription from your doctor.

• Viagra cream is considered experimental by many health authorities.
• It is not approved by the FDA for medical use.
• Efficacy evidence mainly comes from anecdotal reports.
• Risks associated include allergic reactions and skin burns.
• It can be part of a broader treatment plan for ED.
• Safe disposal of unused cream is necessary to prevent misuse.
• The cream may interact with other medications, demanding caution.
• Clinical trials are needed to confirm safety and efficiency.
• Patients should report adverse effects promptly.
• Distribution channels are often unregulated, so caution is advised.

Daré Bioscience is collaborating with a telehealth provider through its dispensing pharmacy, Medvantx, which can write a script for women with any arousal difficulties. Dare to Play, which has a shelf life of four years, is being offered as a compounded drug manufactured at an FDA-registered 503B outsourcing facility. Residents of Connecticut, Florida, Indiana, Missouri, New Hampshire, New Jersey, Oregon, Pennsylvania, Rhode Island and Utah can pre-order it now. Prescriptions are expected to be filled in all US states in early 2026.

Daré Bioscience is also pursuing full FDA approval.

The Bottom Line

Customer service was quick, pleasant, and attentive. I received my package in 5 days with no issues. Thank you WISP for an awesome product. cream, and I went to the site, filled out the questionnaire and within 3 days it showed up at my house. I didn’t have time to go to the doc to get antibiotics and they were at Walgreens for me hours later! “Last summer, our data [were] published about the studies that have been completed, and we started getting really overwhelming requests from women and health care providers to make the formulation available,” Johnson said. “We were able, as a company, to identify a dual-path approach to really meet that demand and meet women where they are,” she added.

Individual Solutions

See more of our coverage in your search results. For nearly three decades, Viagra has helped men rise to the occasion. The little blue pill increases blood flow to the penis, making it easier to get and keep erections. But women have been left out in the cold, with no real pharmaceutical fix for low libido — until now. In a sultry twist, Viagra’s secret sauce has been reimagined to boost women’s arousal. “We can make the product available as a compounded product, but under a specific kind of facility that follows FDA inspection and FDA manufacturing practices and make that available for prescription now, while we continue the process with the FDA,” Johnson explained. Daré Bioscience is working with the FDA on a plan for a Phase 3 study — a 12-week double-blind trial that will compare Dare to Play to a placebo cream.

Publication types

A New Topical Drug Delivery Platform: The Examples of Sildenafil and Ibuprofen. 11 American College of Obstetricians and Gynecologists. Preliminary efficacy of topical sildenafil cream for the treatment of female sexual arousal disorder [podcast episode]. The Green Room: A Podcast from Obstetrics & Gynecology. This product has not been reviewed by FDA for safety or efficacy.

Plast Reconstr Surg

DARE to PLAY Sildenafil Cream is manufactured in a 503B outsourcing facility under pharmaceutical Good Manufacturing Practices (GMP). Per month for 3 months Choose a one-time treatment or subscription Featuring Sildenafil, Viagra’s active ingredient, now in Original & Extra Strength. Cream is a lightweight, topical prescription cream that helps increase blood flow to the clitoris. The magic ingredient, Sildenafil (generic Viagra), aids in arousal and sensation for better, wetter orgasms—now available in our Original 1% formula and a new Extra Strength formula with 3% Sildenafil for an even bigger boost. Cream can be a gamechanger for folks struggling with arousal at any stage of their life.

Increased sexual response in a cream

All orgasms are not created equal—whether you need help getting started, rev'ing up, or crossing the finish line, OMG! WISP pricing of the OMG is the lowest found. I was approved for prescription OMG within 24 hrs of filling out the form. It arrived quickly in the mail in discreet packaging. After applying the cream within 15 minutes my libido soared and vaginal dryness was no longer a problem. Johnson noted that Viagra has been FDA-approved since 1998, but there’s no equivalent FDA-approved product for women — even though their struggles are just as real.

How It Works

Diagnostic and Statistical Manual of Mental Disorders. The evolution of the female sexual disorder/dysfunction definitions, nomenclature, and classifications: a review of DSM, ICSM, ISSWSH, and ICD. doi: 10.1016/j.sxmr.2020.05.001 3 16% of women in the U.S. ages 21-60 are distressed from experiencing no or low sexual arousal, according to market research, and are actively seeking treatment. Ad Hoc Market Research: FSAD Prevalence Report (Oct 2015) conducted for SST LLC and based on US Census projections for 2016.

Why is clitoral stimulation for orgasm more important during menopause?

4 Thurman AR, Johnson I, Cornell KA, Hatheway J, Kim NN, Parish SJ, Dart C, Friend DR, Goldstein A. Safety of topical sildenafil cream, 3.6% in a randomized, placebo-controlled trial for the treatment of female sexual arousal disorder. 2024;21(9):793-799. doi:10.1093/jsxmed/qdae089 5 Goldstein S, Kukkonen T, Monsef A, Goldstein I. A double-blind, placebo-controlled, 2-way crossover study using thermography to assess the pharmacodynamics of sildenafil cream, 3.6% in healthy women.

Wisp Company Reviews

doi:10.1016/j.jsxm.2019.11.194 6 Johnson I, Thurman AR, Cornell KA, Hatheway J, Dart C, Brainard CP, Friend DR, Goldstein A. Preliminary efficacy of topical sildenafil cream for the treatment of female sexual arousal disorder: A randomized, placebo‑controlled, Phase 2b trial. Impact of age, race, and medication use on efficacy endpoints in a randomized controlled trial of topical sildenafil cream for the treatment of female sexual arousal disorder. Comparisons and correlations of 1‑month recall vs 24‑hour recall in patient‑reported outcomes of an exploratory, phase 2b, randomized, double‑blind, placebo‑controlled clinical trial of sildenafil cream, 3.6% for the treatment of female sexual arousal disorder. Symptoms and associated impact in pre‑ and postmenopausal women with sexual arousal disorder: a concept elicitation study. Products that claim to improve female arousal “are really relying heavily on marketing language, consumer reviews, lifestyle branding, without the real evidence,” Johnson said.